Neil received his MD and PhD from The University of Toronto. He completed his anesthesia residency at The University of Toronto within the Clinician-Investigator Program, and carried out a postdoctoral fellowship under Dr. Wolfgang Kuebler at St. Michael’s Hospital. Neil then finished a clinical fellowship in pediatric anesthesia at The Hospital for Sick Children.
Neil’s laboratory group studies pulmonary vascular inflammation. Pulmonary hypertension is a devastating disease of the lung vasculature, arising from a variety of conditions, which carries a high overall and perioperative mortality rate. Neil’s research uses patient-derived tissues, as well as translational rodent and in vitro model systems to investigate the immunological underpinnings of this disease. Specifically, we investigate the involvement of B cell dysfunction and autoimmunity, as well as macrophage biology, in the pathogenesis of pulmonary hypertension. Our central aim is to deepen our understanding of the immunobiology of pulmonary hypertension with an eye toward developing novel immune-therapeutics for this disease.