My most significant contribution has been in generating evidence to prevent postoperative events in patients with obstructive sleep apnea (OSA). My work systematically addressed the early screening for OSA, diagnostic methods and perioperative management. For knowledge translation, I was the Founding Chair of Society of Anesthesia and Sleep Medicine (http://sasmhq.org/) (2010/11), President Elect 2011-13 and President 2013-15. I have established myself as an expert in the area, (h-index:73) and I hold the ResMed Inaugural Research Chair of Anesthesiology, Sleep Medicine at University of Toronto. My major contributions are:
1. Development of the STOP-Bang questionnaire (www.stopbang.ca); a validated and user-friendly tool to screen for OSA in different populations.
Chung F et al. STOP Questionnaire: A tool to screen patients for OSA. Anesthesiology. 2008; 108:812-21. It is a guideline-recommended OSA screening tool in patients with suspected OSA. Web of Science, citation 841 .
Chung F et al. High STOP-Bang score indicates a high probability of OSA. Br J Anaesth. 2012; 108: 768–775. This publication on STOP-Bang score was chosen as one of the top 25 key papers of major importance and contribution to the field of anesthesia in the history of anesthesia by British Journal of Anaesthesia. Web of Science, citation 330. https://www.ncbi.nlm.nih.gov/pubmed/22401881
I chaired the International 28 member Task Force of Society of Anesthesia and Sleep Medicine to develop 2016 “Guidelines on Preoperative Screening and Assessment of Patients with OSA”. 1st Author, Anesth Analg 2016;123:452-73.
2. Co-Chair and senior author: International POSA trial group on “Postoperative Vascular Events in Unrecognized OSA (POSA)”. We completed the POSA study to determine the associations between OSA, and major postoperative CV events in 1,218 moderate-to-high cardiac risk patients undergoing major noncardiac surgery. We determine that undiagnosed surgical patients have higher risk of postoperative cardiovascular complications.
Chan MT…Chung F. Association of Unrecognized Obstructive Sleep Apnea With Postoperative Cardiovascular Events in Patients Undergoing Major Noncardiac Surgery. JAMA. 2019. https://jamanetwork.com/journals/jama/fullarticle/2733209
3. Co-Chair and senior author: Research Priorities Workshop for “Knowledge Gaps in the Perioperative Management of Adults with OSA and Obesity Hypoventilation Syndrome” at the 2016 American Thoracic Society Conference. Conclusion: Further research is urgently needed to improve health outcomes and reduce health care costs. Annals of American Thoracic Society 2018; 15:117-26.
4. Co-Chair and senior author: Task Force of the Society of Anesthesia and Sleep Medicine Guidelines on Intraoperative Management of Adult Patients with OSA. Society of Anesthesia and Sleep Medicine Guideline on Intraoperative management of adult patients with OSA. Anesth Analg. https://www.ncbi.nlm.nih.gov/pubmed/29944522